GMPS Antibody
Product Specifications
Background
In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.
NCBI Gene ID
8833
Swiss Prot
P49915
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 394-693 of human GMPS (NP_003866.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
MCF-7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 80kDa
Fragment
IgG
Symbol
GMPS
Positive Control 2
SKOV3
Positive Control 3
HL-60
Positive Control 4
U-251MG
Positive Control 5
Mouse heart
Positive Control 6
Mouse kidney
NCBI Official Name
Guanine monphosphate synthase
NCBI Organism
Homo sapiens
Other Product Names
GMPS
Tested Applications
WB, IP
Physical Properties
Liquid
Curated Selection
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