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GBE1 Antibody

Product Specifications

Background

The protein encoded by this gene is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease) .

NCBI Gene ID

2632

Swiss Prot

Q04446

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GBE1 (NP_000149.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 80kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

GBE1

Positive Control 2

NCI-H460

Positive Control 3

Mouse heart

Positive Control 4

Mouse liver

Positive Control 5

Mouse kidney

Positive Control 6

Rat liver

NCBI Official Name

1,4-alpha-glucan-branching enzyme

NCBI Organism

Homo sapiens

Other Product Names

4-alpha-glucan-branching enzyme, Brancher enzyme, Glycogen-branching enzyme, GBE1

Tested Applications

WB

Physical Properties

Liquid

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