GATM Antibody
Product Specifications
Background
This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.
NCBI Gene ID
2628
Swiss Prot
P50440
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 124-423 of human GATM (NP_001473.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse kidney
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 43kDa
Fragment
IgG
Symbol
GATM
Positive Control 2
Rat kidney
NCBI Official Name
Glycine amidinotransferase (L-arginine:glycine amidinotransferase)
NCBI Organism
Homo sapiens
Other Product Names
GATM, AGAT, AT, CCDS3
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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037005-PE 200 µL
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