CCT5 Antibody
Product Specifications
Background
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP) . Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13.
NCBI Gene ID
22948
Swiss Prot
P48643
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CCT5 (NP_036205.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 60kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CCT5
Positive Control 2
BT-474
Positive Control 3
MCF7
Positive Control 4
U-937
Positive Control 5
Mouse spleen
Positive Control 6
Mouse thymus
NCBI Official Name
Chaperonin containing TCP1, subunit 5 (epsilon)
NCBI Organism
Homo sapiens
Other Product Names
CCT5, CCT-epsilon, CCTE, KIAA0098, TCP-1-epsilon, HEL-S-69
Tested Applications
WB
Physical Properties
Liquid
Frequently Asked Questions
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