GLI2 Antibody
Product Specifications
Background
This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.
NCBI Gene ID
14633
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant protein of mouse GLI2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction, Stem Cell, Transcription
Purification
Affinity purification
Positive Control
Mouse lung
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 90kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
GLI2
Positive Control 2
Mouse brain
Positive Control 3
Mouse heart
Positive Control 4
Mouse ovary
Positive Control 5
Mouse pancreas
Positive Control 6
Rat brain
NCBI Official Name
GLI-Kruppel family member GLI2
NCBI Organism
Mus musculus
Other Product Names
Zinc finger protein GLI2, Tax helper protein
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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