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POLR3K Antibody

Product Specifications

Background

This gene encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor. This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription. Pseudogenes of this gene are found on chromosomes 13 and 17.

NCBI Gene ID

51728

Swiss Prot

Q9Y2Y1

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human POLR3K (NP_057394.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

MCF7

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 12kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

POLR3K

Positive Control 2

SW620

NCBI Official Name

RNA polymerase III subunit K

NCBI Organism

Homo sapiens

Other Product Names

C11, C11-RNP3, My01RPC1RPC11, RPC12.5, DNA-directed RNA polymerase III subunit RPC1DNA-directed RNA polymerase III subunit K, DNA-directed RNA polymerases III 12.5 kDa polypeptide, RNA polymerase III 12.5 kDa subunit, RNA polymerase III subunit C1RNA polymerase III subunit C11, RNA polymerase III subunit CII, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa, polymerase (RNA) III subunit K

Tested Applications

WB

Physical Properties

Liquid

Frequently Asked Questions

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