POLR3K Antibody
Product Specifications
Background
This gene encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor. This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription. Pseudogenes of this gene are found on chromosomes 13 and 17.
NCBI Gene ID
51728
Swiss Prot
Q9Y2Y1
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human POLR3K (NP_057394.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 12kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
POLR3K
Positive Control 2
SW620
NCBI Official Name
RNA polymerase III subunit K
NCBI Organism
Homo sapiens
Other Product Names
C11, C11-RNP3, My01RPC1RPC11, RPC12.5, DNA-directed RNA polymerase III subunit RPC1DNA-directed RNA polymerase III subunit K, DNA-directed RNA polymerases III 12.5 kDa polypeptide, RNA polymerase III 12.5 kDa subunit, RNA polymerase III subunit C1RNA polymerase III subunit C11, RNA polymerase III subunit CII, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa, polymerase (RNA) III subunit K
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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