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Anti-KLH | Keyhole limpet hemocyanin, DyLight® 488 conjugated (40 µg)

Selected Variant

AS99 001-DL488

Size: 40 µg

Product Specifications

Background

Keyhole limpet hemocyanin (KLH) is a large cooper-containing protein consisting of subunits with MW of 400 kDa, It is found in the hemolymph of the sea mollusk Megathura crenulata, This extracellular respiratory protein has many immunostimulatory properties, including the ability to enhance the host's immune response by interacting with T cells, monocytes, macrophages, and polymorphonuclear lymphocytes, Since its discovery, KLH has been used primarily as a carrier for vaccines and antigens and as adjuvant treatment in regimens such as antimicrobial therapy.

CAS Number

9007-83-4

HS Code

38221900

UniProt

Q6KC56

Host

Rabbit

Reactivity

KLH from Megathura crenulata

Not reactive in

No confirmed exceptions from predicted reactivity are currently known.

Immunogen

Purified keyhole limpet hemocyanin (KLH), whole molecule.

Clonality

Polyclonal

Applications

Immunofluorescence (IF), Western blot (WB)

Field of Research

Carrier Proteins

Dilution

To be determined by end user.

Purity

Immunogen affinity purified serum, in PBS pH 7.4, conjugated to DyLight® 488.

Format

Liquid in PBS pH 7,4.

Molecular Weight

Ca. 400 kDa/subunit

Additionnal Information

Protein present in plant vascular tissue (xylem and vascular cambium) is detected by anti-KLH antibodies (Höglund et al, 2002) which might lead to false results in IL when using anti-peptide antibodies generated to KLH-conjugated peptide.DyLight® 488 Amax = 493 nm, Emax = 519 nm. DyLight® is a registered trademark of Thermofisher Inc., and its subsidiaries.

References & Citations

To be added when available. Antibody released in May 2023.

Storage Conditions

Store at 4°C for 12-18 months, A preservative may be added for long time storage up to 2 years. Spin briefly the tube before use.

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