TNFAIP6 Antibody
Product Specifications
Background
The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.
NCBI Gene ID
7130
Swiss Prot
P98066
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 18-277 of human TNFAIP6 (NP_009046.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Innate Immunity, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse brain
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=22-206
Calculated Molecular Weight
Observed: 40kDa
Fragment
IgG
Symbol
TNFAIP6
NCBI Official Name
Tumor necrosis factor, alpha-induced protein 6
NCBI Organism
Homo sapiens
Other Product Names
TSG6, Tumor necrosis factor-inducible gene 6 protein, Hyaluronate-binding protein, TSG-6, TSG6, Tumor necrosis factorinducible protein TSG6, TNF-stimulated gene 6 protein
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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