SSRP1 Antibody
Product Specifications
Background
The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
NCBI Gene ID
6749
Swiss Prot
Q08945
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SSRP1 (NP_003137.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Affinity purification
Positive Control
HT-29
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 98kDa
Fragment
IgG
Symbol
SSRP1
Positive Control 2
SW620
Positive Control 3
HeLa
NCBI Official Name
Structure specific recognition protein 1
NCBI Organism
Homo sapiens
Other Product Names
SSRP1, FACT, FACT80, T160
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6153359-01 0.1 mL
LRRC4C (KIAA1580, NGL1, Leucine-rich Repeat-containing Protein 4C, Netrin-G1 Ligand)) (HRP)
Ask
View Details 
MBS6153359-02 5x 0.1 mL
LRRC4C (KIAA1580, NGL1, Leucine-rich Repeat-containing Protein 4C, Netrin-G1 Ligand)) (HRP)
Ask
View Details 