PYGB Antibody
Product Specifications
Background
The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.
NCBI Gene ID
5834
Swiss Prot
P11216
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 544-843 of human PYGB (NP_002853.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
BT-474
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 105kDa
Fragment
IgG
Symbol
PYGB
Positive Control 2
SW620
Positive Control 3
HT-29
Positive Control 4
HepG2
Positive Control 5
Mouse brain
Positive Control 6
Mouse heart
NCBI Official Name
Phosphorylase, glycogen; brain
NCBI Organism
Homo sapiens
Other Product Names
PYGB, GPBB, Phosphorylase, glycogen, Phosphorylase, glycogen brain, Glycogen phosphorylase B
Tested Applications
WB, IF, IP
Physical Properties
Liquid
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