PPOX Antibody
Product Specifications
Background
This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
NCBI Gene ID
5498
Swiss Prot
P50336
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PPOX (NP_001116236.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 51kDa
Fragment
IgG
Symbol
PPOX
Positive Control 2
Mouse spleen
Positive Control 3
Mouse liver
Positive Control 4
Mouse kidney
NCBI Official Name
Protoporphyrinogen oxidase
NCBI Organism
Homo sapiens
Other Product Names
PPO, V290M, VP, protoporphyrinogen oxidase
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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