Duclauxin
Duclauxin decreases proliferation of tumor cells in vitro and increases the lifespan of mice innoculated with Ehrlich ascitic tumor cells. Duclauxin (10-30 μg/mL) inhibits mitochondrial respiration of P-388 tumor cells and nucleic acid synthesis in cell culture of Ehrlich cancer, the lymphadenomas NK/LI and L 5178, and sarcoma 37. Duclauxin also inhibits growth of wheat coleoptile.
Product Specifications
CAS Number
1732-37-2
Product Name Alternative
NSC 258308
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/duclauxin.html
Smiles
O=C1C2=C(O)C=C(C)C3=C2[C@]4([C@@]([C@]5(OC)[C@@]([C@H]4OC(C)=O)([H])C3=O)([H])C(C6=COC(C7=C(O)C=C(C)C5=C76)=O)=O)CO1
Molecular Formula
C29H22O11
Molecular Weight
546.48
References & Citations
[1]Fusková, et al. In vitro effect of duclauxin and derivatives of coumarin on nucleic acid and protein synthesis in Ehrlich’s Ascites Carcinoma cells (EAC) . Pharmazie 32 (5), 291-293 (1977) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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