LIMS1 Antibody
Product Specifications
Background
The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
3987
Swiss Prot
P48059
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human LIMS1 (NP_001180417.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Growth Factors, Signal Transduction
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=22-176
Calculated Molecular Weight
Observed: 40kDa
Fragment
IgG
Symbol
LIMS1
NCBI Official Name
LIM zinc finger domain containing 1
NCBI Organism
Homo sapiens
Other Product Names
PINCH, PINCH-1, PINCH1, LIM and senescent cell antigen-like-containing domain protein 1, LIM and senescent cell antigen-like domains 1, LIM-type zinc finger domains 1, particularly interesting new Cys-His protein 1, renal carcinoma antigen NY-REN-48, senescent cell antigen
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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