GRP Antibody

Product Specifications

Background

This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. The encoded preproprotein is proteolytically processed to generate two peptides, gastrin-releasing peptide and neuromedin-C. These peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

NCBI Gene ID

2922

Swiss Prot

P07492

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-148 of human GRP (NP_002082.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Growth Factors, Signal Transduction

Purification

Affinity purification

Positive Control

Mouse lung

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 16kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

GRP

Positive Control 2

Mouse spinal cord

Positive Control 3

Rat brain

Positive Control 4

Rat kidney

NCBI Official Name

Gastrin releasing peptide

NCBI Organism

Homo sapiens

Other Product Names

BN-1preproGRP, proGRP, GRP, gastrin-releasing peptide, bombesin, neuromedin C, pre-progastrin releasing peptide, prepro-GRP, testicular tissue protein Li 103