DBN1 Antibody

Product Specifications

Background

The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.

NCBI Gene ID

1627

Swiss Prot

Q16643

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 350-649 of human DBN1 (NP_004386.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

BT-474

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 110kDa

Fragment

IgG

Symbol

DBN1

Positive Control 2

HeLa

Positive Control 3

SKOV3

NCBI Official Name

Drebrin

NCBI Organism

Homo sapiens

Other Product Names

Drebrin, Developmentally-regulated brain protein, DBN1, D0S117E

Tested Applications

WB, IF

Physical Properties

Liquid

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