RHOH Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP) -metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein.
NCBI Gene ID
399
Swiss Prot
Q15669
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human RHOH (NP_004301.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
BT-474
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 27kDa
Fragment
IgG
Symbol
RHOH
Positive Control 2
SW620
Positive Control 3
Jurkat
Positive Control 4
HT-29
Positive Control 5
Mouse spleen
Positive Control 6
Mouse thymus
NCBI Official Name
Rho-related GTP-binding protein RhoH
NCBI Organism
Homo sapiens
Other Product Names
Rho-related GTP-binding protein RhoH, GTP-binding protein TTF, Translocation three four protein, RHOH, ARHH, TTF
Tested Applications
WB, IF
Physical Properties
Liquid
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