ZC3HC1 Antibody

Product Specifications

Background

This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis.

NCBI Gene ID

51530

Swiss Prot

Q86WB0

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ZC3HC1 (NP_057562.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 55kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

ZC3HC1

NCBI Official Name

Zinc finger C3HC-type containing 1

NCBI Organism

Homo sapiens

Other Product Names

HSPC216, NIPA, nuclear-interacting partner of ALK, hematopoietic stem/progenitor cell protein 216, nuclear interacting partner of anaplastic lymphoma kinase (ALK)