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SERPINA7 Antibody

Product Specifications

Background

There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

NCBI Gene ID

6906

Swiss Prot

P05543

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 146-415 of human SERPINA7 (NP_000345.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Growth Factors, Signal Transduction

Purification

Affinity purification

Positive Control

Muose heart

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 46kDa

Fragment

IgG

Symbol

SERPINA7

Positive Control 2

Mouse pancreas

Positive Control 3

Rat liver

Positive Control 4

Rat kidney

NCBI Official Name

Thyroxine-binding globulin

NCBI Organism

Homo sapiens

Other Product Names

Thyroxine-binding globulin, Serpin A7, T4-binding globulin, SERPINA7, TBG

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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