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PGM1 Antibody

Product Specifications

Background

The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.

NCBI Gene ID

5236

Swiss Prot

P36871

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PGM1 (NP_002624.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

U-251MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 61kDa

Fragment

IgG

Symbol

PGM1

Positive Control 2

HepG2

Positive Control 3

293T

Positive Control 4

Mouse liver

Positive Control 5

Mouse heart

Positive Control 6

Rat liver

NCBI Official Name

Phosphoglucomutase-1

NCBI Organism

Homo sapiens

Other Product Names

Phosphoglucomutase-1, PGM 1, Glucose phosphomutase 1, PGM1

Tested Applications

WB, IF

Physical Properties

Liquid

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