GZMA Antibody

Product Specifications

Background

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.

NCBI Gene ID

3001

Swiss Prot

P12544

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 29-262 of human GZMA (NP_006135.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle, Immunology, Innate Immunity

Purification

Affinity purification

Positive Control

Mouse spleen

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 35kDa

Fragment

IgG

Symbol

GZMA

Positive Control 2

Mouse thymus

Positive Control 3

Rat intestine

Positive Control 4

Rat spleen

NCBI Official Name

Granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)

NCBI Organism

Homo sapiens

Other Product Names

GZMA, granzyme A, Hanukah factor serine protease), Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3, CTL tryptase, HFSP, CTLA3, granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3), GZMA