CYP2C9 Antibody
Product Specifications
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.
NCBI Gene ID
1559
Swiss Prot
P11712
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 211-490 of human CYP2C9 (NP_000762.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 63kDa
Fragment
IgG
Symbol
CYP2C9
Positive Control 2
MCF7
Positive Control 3
U-937
Positive Control 4
HepG2
Positive Control 5
22Rv1
Positive Control 6
Raji
NCBI Official Name
Cytochrome P450, family 2, subfamily C, polypeptide 9
NCBI Organism
Homo sapiens
Other Product Names
CYP2C9, CPC9, CYP2C, CYP2C10, MGC149605, MGC88320, P450 MP-4, P450 PB-1, P450IIC9, CYPIIC9
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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