IL31RA Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR) . Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

NCBI Gene ID

133396

Swiss Prot

Q8NI17

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IL31RA (NP_001229568.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle, Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction

Purification

Affinity purification

Positive Control

Mouse liver

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 83kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

IL31RA

Positive Control 2

Mouse heart

Positive Control 3

Mouse brain

Positive Control 4

Mouse pancreas

NCBI Official Name

Interleukin 31 receptor A

NCBI Organism

Homo sapiens

Other Product Names

CRL, CRL3, GLM-R, GLMR, GPL, IL-31RA, PLCA2, PRO21384, hGLM-R, interleukin-31 receptor subunit alpha, IL-31 receptor subunit alpha, IL-31R subunit alpha, class I cytokine receptor, cytokine receptor-like 3, gp130-like monocyte receptor, soluble type I cytokine receptor CRL3, zcytoR17