Anti IL1RL1/ST2 (STLM208) - Research Grade Biosimilar
Product Specifications
Background
This product is a recombinant human antibody that recognizes IL1RL1. The antibody was expressed in mammalian cells with chemically defined culture media and was purified by affinity chromatography. Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.
NCBI Gene ID
9173
Swiss Prot
Q01638
Accession Number
Q01638
Immunogen
Humanized / IL1RL1/ST2 [Homo sapiens]
Clonality
Recombinant Monoclonal
Conjugation
Unconjugated
Type
Primary Antibodies, Biosimilars
Source
CHO cells
Field of Research
Other
Purification
>95%
Concentration
Batch dependent
Purity
>95%
Buffer
PBS buffer pH 7.5
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at +4°C short term (1-2 weeks) . Store at -20 °C 12 months. Store at -80°C long term.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=21-876
Fragment
Human IgG
Symbol
IL1RL1
NCBI Official Name
Interleukin 1 receptor like 1
NCBI Organism
Homo sapiens
Other Product Names
STLM208, T1; ST2; DER4; ST2L; ST2V; FIT-1; IL33R
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