NHP2 Antibody

Product Specifications

Background

This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

55651

Swiss Prot

Q9NX24

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-153 of human NHP2 (NP_060308.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

293T

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 17kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

NHP2

Positive Control 2

HeLa

NCBI Official Name

NHP2 ribonucleoprotein

NCBI Organism

Homo sapiens

Other Product Names

DKCB2P, NOLA2, NHP2, H/ACA ribonucleoprotein complex subunit 2, NHP2 ribonucleoprotein homolog, NHP2-like protein, nucleolar protein family A, member 2 (H/ACA small nucleolar RNPs), snoRNP protein NHP2