POP1 Antibody

Product Specifications

Background

This gene encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

10940

Swiss Prot

Q99575

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human POP1 (NP_055844.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Inflammasomes

Purification

Affinity purification

Positive Control

Mouse liver

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 115kDa

Fragment

IgG

Applications Notes

WB: 1:200 - 1:2000

Symbol

POP1

Positive Control 2

Mouse kidney

Positive Control 3

Rat liver

NCBI Official Name

POP1 homolog, ribonuclease P/MRP subunit

NCBI Organism

Homo sapiens

Other Product Names

ANXD2, ribonucleases P/MRP protein subunit POP1, hPOP1, processing of precursor 1, ribonuclease P/MRP subunit, processing of precursors 1

Tested Applications

Physical Properties

Liquid

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