POLR2B Antibody
Product Specifications
Background
This gene encodes the second largest subunit of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into precursors of mRNA, snRNA and microRNA. This subunit and the largest subunit form opposite sides of the center cleft of Pol II. Deletion of the flap loop region of this subunit results in a decrease in the rate of transcriptional elongation. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
5431
Swiss Prot
P30876
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human POLR2B (NP_000929.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Affinity purification
Positive Control
SH-SY5Y
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 134kDa
Fragment
IgG
Symbol
POLR2B
Positive Control 2
A375
Positive Control 3
HepG2
Positive Control 4
BT-474
Positive Control 5
Mouse brain
Positive Control 6
Mouse spleen
NCBI Official Name
Polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
NCBI Organism
Homo sapiens
Other Product Names
POLR2B, RPB2, POL2RB, hsRPB2, hRPB140
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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