ETF1 Antibody

Product Specifications

Background

This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD) . Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X.

NCBI Gene ID

2107

Swiss Prot

P62495

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 278-437 of human ETF1 (NP_004721.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

Raji

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 55kDa

Fragment

IgG

Symbol

ETF1

Positive Control 2

U-87MG

Positive Control 3

HT-1080

Positive Control 4

SKOV3

Positive Control 5

Mouse liver

Positive Control 6

Mouse heart

NCBI Official Name

Eukaryotic translation termination factor 1

NCBI Organism

Homo sapiens

Other Product Names

D5S1995, ERF, ERF1, RF1, SUP45L1, TB3-1, eukaryotic peptide chain release factor subunit 1, polypeptide chain release factor 1, protein Cl1, sup45 (yeast omnipotent suppressor 45) homolog-like 1