CTSK Antibody
Product Specifications
Background
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.
NCBI Gene ID
1513
Swiss Prot
P43235
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 115-329 of human CTSK (NP_000387.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
A-431
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 37kDa
Fragment
IgG
Symbol
CTSK
Positive Control 2
HeLa
NCBI Official Name
Cathepsin K
NCBI Organism
Homo sapiens
Other Product Names
CTSK, cathepsin K, CTS02, CTSO, CTSO1, CTSO2, MGC23107, PKND, PYCD, cathepsin K (pycnodysostosis), cathepsin O1, cathepsin O2, cathepsin X
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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