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MRPS30 Antibody

Product Specifications

Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that is similar to the chicken pro-apoptotic protein p52. Transcript variants using alternative promoters or polyA sites have been mentioned in the literature but the complete description of these sequences is not available.

NCBI Gene ID

10884

Swiss Prot

Q9NP92

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 190-439 of human MRPS30 (NP_057724.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle

Purification

Affinity purification

Positive Control

SW620

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 54kDa

Fragment

IgG

Symbol

MRPS30

Positive Control 2

HL-60

Positive Control 3

HeLa

Positive Control 4

HepG2

NCBI Official Name

Mitochondrial ribosomal protein S30

NCBI Organism

Homo sapiens

Other Product Names

MRP-S3PAP, PDCD9, S30mt, 39S ribosomal protein S3mitochondrial, 28S ribosomal protein S3mitochondrial, mitochondrial large ribosomal subunit protein mL65, mitochondrial large ribosomal subunit protein mS3programmed cell death 9

Tested Applications

WB, IHC, IF, IP

Physical Properties

Liquid

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