MRPS30 Antibody
Product Specifications
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that is similar to the chicken pro-apoptotic protein p52. Transcript variants using alternative promoters or polyA sites have been mentioned in the literature but the complete description of these sequences is not available.
NCBI Gene ID
10884
Swiss Prot
Q9NP92
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 190-439 of human MRPS30 (NP_057724.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle
Purification
Affinity purification
Positive Control
SW620
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 54kDa
Fragment
IgG
Symbol
MRPS30
Positive Control 2
HL-60
Positive Control 3
HeLa
Positive Control 4
HepG2
NCBI Official Name
Mitochondrial ribosomal protein S30
NCBI Organism
Homo sapiens
Other Product Names
MRP-S3PAP, PDCD9, S30mt, 39S ribosomal protein S3mitochondrial, 28S ribosomal protein S3mitochondrial, mitochondrial large ribosomal subunit protein mL65, mitochondrial large ribosomal subunit protein mS3programmed cell death 9
Tested Applications
WB, IHC, IF, IP
Physical Properties
Liquid
Curated Selection
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