PRODH Antibody

Product Specifications

Background

This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4) . This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

5625

Swiss Prot

O43272

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 321-600 of human PRODH (NP_057419.4) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

BT-474

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 68kDa

Fragment

IgG

Symbol

PRODH

Positive Control 2

MCF-7

Positive Control 3

U-251MG

Positive Control 4

A-673

Positive Control 5

Mouse liver

Positive Control 6

Mouse kidney

NCBI Official Name

Proline dehydrogenase (oxidase) 1

NCBI Organism

Homo sapiens

Other Product Names

PRODH, tumor protein p53 inducible protein 6, TP53I6, SCZD4, proline oxidase, mitochondrial, proline oxidase 2, proline dehydrogenase, proline dehydrogenase (oxidase) 1, PRODH2, PRODH1, POX, PIG6, p53-induced gene 6 protein, OTTHUMP00000196497, OTTHUMP00000196496, MGC148079, MGC148078, HSPOX2, FLJ33744, POX2