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GRO alpha Antibody

Product Specifications

Background

This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.

NCBI Gene ID

2919

Swiss Prot

P09341

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-107 of human GRO alpha (NP_001502.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Innate Immunity

Purification

Affinity purification

Positive Control

DU145

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 11kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

CXCL1

NCBI Official Name

Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)

NCBI Organism

Homo sapiens

Other Product Names

CXCL1, GRO1, GROa, MGSA, MGSA alpha, MGSA-a, NAP-3, SCYB1, FSP

Tested Applications

WB

Physical Properties

Liquid

Frequently Asked Questions

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