PPP2R1A Antibody
Product Specifications
Background
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.
NCBI Gene ID
5518
Swiss Prot
P30153
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human PPP2R1A (NP_055040.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
SKOV3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 65kDa
Fragment
IgG
Symbol
PPP2R1A
Positive Control 2
293T
Positive Control 3
HepG2
Positive Control 4
MCF7
Positive Control 5
HL-60
Positive Control 6
Mouse brain
NCBI Official Name
Protein phosphatase 2, regulatory subunit A, alpha
NCBI Organism
Homo sapiens
Other Product Names
PPP2R1A, MGC786, PR65A, PP2AAALPHA, PP2A-Aalpha
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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