NFKBIB Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
NCBI Gene ID
4793
Swiss Prot
Q15653
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-356 of human NFKBIB (NP_002494.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Immunology, Innate Immunity, Signal Transduction, Transcription
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 40-50kDa
Fragment
IgG
Symbol
NFKBIB
Positive Control 2
293T
Positive Control 3
Mouse liver
Positive Control 4
Mouse skeletal muscle
NCBI Official Name
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NCBI Organism
Homo sapiens
Other Product Names
NFKBIB, IKBB, TRIP9
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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