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BGN Antibody

Product Specifications

Background

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication.

NCBI Gene ID

633

Swiss Prot

P21810

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 38-368 of human BGN (NP_001702.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

Mouse heart

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 43kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

BGN

Positive Control 2

Mouse skeletal muscle

NCBI Official Name

Biglycan

NCBI Organism

Homo sapiens

Other Product Names

BGN, biglycan, DSPG1, PG-S1, PGI, SLRR1A, bone/cartilage proteoglycan-I, dermatan sulphate proteoglycan I, small leucine-rich protein 1A

Tested Applications

WB

Physical Properties

Liquid

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