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Heparanase 1 Antibody

Product Specifications

Background

Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. The protein encoded by this gene is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition, this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

10855

Swiss Prot

Q9Y251

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 36-275 of human Heparanase 1 (NP_001092010.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 50kDa/65kDa

Fragment

IgG

Symbol

HPSE

Positive Control 2

HepG2

Positive Control 3

Jurkat

Positive Control 4

Mouse spleen

Positive Control 5

Mouse thymus

Positive Control 6

Mouse lung

NCBI Official Name

Heparanase

NCBI Organism

Homo sapiens

Other Product Names

HPSE, Endo-glucoronidase, Heparanase-1, Heparanase, HPA, HSE1, HEP, HPA1, HPSE1, HPR1

Tested Applications

WB, IF

Physical Properties

Liquid

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