CRX Antibody
Product Specifications
Background
The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
NCBI Gene ID
1406
Swiss Prot
O43186
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 120-285 of human CRX (NP_000545.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Transcription
Purification
Affinity purification
Positive Control
Mouse eye
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 37kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CRX
NCBI Official Name
Cone-rod homeobox
NCBI Organism
Homo sapiens
Other Product Names
CRX, cone-rod homeobox, CORD2, CRD, LCA7, OTX3, cone-rod homeobox protein, orthodenticle homeobox 3
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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