CLCN5 Antibody
Product Specifications
Background
This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.
NCBI Gene ID
1184
Swiss Prot
P51795
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 637-816 of human CLCN5 (NP_001121370.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
SW480
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 100kDa
Fragment
IgG
Symbol
CLCN5
Positive Control 2
U-937
Positive Control 3
HepG2
Positive Control 4
A673
Positive Control 5
NCI-H460
Positive Control 6
Mouse kidney
NCBI Official Name
H (+) /Cl (-) exchange transporter 5
NCBI Organism
Homo sapiens
Other Product Names
H (+) /Cl (-) exchange transporter 5, Chloride channel protein 5, ClC-5, Chloride transporter ClC-5, CLCN5, CLCK2
Tested Applications
WB, IF
Physical Properties
Liquid
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