PSMB4 Antibody
Product Specifications
Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.
NCBI Gene ID
5692
Swiss Prot
P28070
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human PSMB4 (NP_002787.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 22kDa
Fragment
IgG
Symbol
PSMB4
Positive Control 2
A375
Positive Control 3
SKOV3
Positive Control 4
U-251MG
Positive Control 5
Mouse thymus
Positive Control 6
Mouse skeletal muscle
NCBI Official Name
Proteasome (prosome, macropain) subunit, beta type, 4
NCBI Organism
Homo sapiens
Other Product Names
PSMB4, HN3, HsN3, PROS26, PROS-26
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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