HPRT1 Antibody, KO Validated
Product Specifications
Background
The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.
NCBI Gene ID
3251
Swiss Prot
P00492
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human HPRT1 (NP_000185.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
MCF-7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 27kDa
Fragment
IgG
Symbol
HPRT1
Positive Control 2
HL-60
Positive Control 3
SW480
Positive Control 4
293T
Positive Control 5
HeLa
Positive Control 6
Mouse brain
NCBI Official Name
Hypoxanthine phosphoribosyltransferase 1
NCBI Organism
Homo sapiens
Other Product Names
HPRT1, HGPRT, HPRT
Tested Applications
WB, IF
Physical Properties
Liquid
Frequently Asked Questions
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