BNIP3 Antibody
Product Specifications
Background
This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation.
NCBI Gene ID
664
Swiss Prot
Q12983
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-164 of human BNIP3 (NP_004043.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Autophagy, Cancer, Cell Cycle
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 22-70kDa
Fragment
IgG
Symbol
BNIP3
Positive Control 2
NCI-H460
Positive Control 3
Jurkat
Positive Control 4
SH-SY5Y
Positive Control 5
Mouse kidney
Positive Control 6
Mouse heart
NCBI Official Name
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
NCBI Organism
Homo sapiens
Other Product Names
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, BNIP3, NIP3
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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