IQGAP1 Antibody
Product Specifications
Background
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.
NCBI Gene ID
8826
Swiss Prot
P46940
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 500-750 of human IQGAP1 (NP_003861.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 189kDa
Fragment
IgG
Symbol
IQGAP1
Positive Control 2
293T
Positive Control 3
HepG2
Positive Control 4
HT-29
Positive Control 5
HeLa
NCBI Official Name
IQ motif containing GTPase activating protein 1
NCBI Organism
Homo sapiens
Other Product Names
RasGAP-like with IQ motifs, p195, SAR1, KIAA0051, HUMORFA01, IQ motif containing GTPase activating protein 1, IQGAP1
Tested Applications
WB, IF
Physical Properties
Liquid
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