GCKR Antibody

Product Specifications

Background

This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY) .

NCBI Gene ID

2646

Swiss Prot

Q14397

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GCKR (NP_001477.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

HL-60

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 60-69kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

GCKR

Positive Control 2

Mouse liver

Positive Control 3

Rat liver

NCBI Official Name

Glucokinase (hexokinase 4) regulator

NCBI Organism

Homo sapiens

Other Product Names

GCKR, glucokinase (hexokinase 4) regulator, GKRP, glucokinase (hexokinase 4) regulatory protein, glucokinase regulator, glucokinase regulatory protein, hexokinase 4, FGQTL5