P53 Activator 3
P53 Activator 3 (compound 87A) is a potent p53 activator with a SC150 value of [1]. p53 Activator 3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
[2636839-90-0]
UNSPSC
12352005
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p53-activator-3.html
Purity
98.35
Solubility
10 mM in DMSO
Smiles
OCCOC1=CC(S(C)(=O)=O)=CC=C1NCC#CC2=CC3=C(C=CC=C3N[C@@H]4CC[C@H](CC4)N(C)C)N2CC(F)(F)F
Molecular Formula
C30H37F3N4O4S
Molecular Weight
606.70
References & Citations
[1]VU, Binh, et al. Methods and compounds for restoring mutant p53 function, WO2021061643.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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