FGG Antibody
Product Specifications
Background
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms.
NCBI Gene ID
2266
Swiss Prot
P02679
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 50-330 of human FGG (NP_000500.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
SGC-996
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=19-773
Calculated Molecular Weight
Observed: 53kDa
Fragment
IgG
Symbol
FGG
Positive Control 2
Mouse liver
Positive Control 3
Mouse lung
NCBI Official Name
Fibrinogen gamma chain
NCBI Organism
Homo sapiens
Other Product Names
FGG
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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