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CTNNA1 Antibody

Product Specifications

Background

This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy.

NCBI Gene ID

1495

Swiss Prot

P35221

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 637-906 of human CTNNA1 (NP_001894.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

BT-474

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=19-768

Calculated Molecular Weight

Observed: 115kDa

Fragment

IgG

Symbol

CTNNA1

Positive Control 2

OVCAR3

Positive Control 3

293T

Positive Control 4

MCF7

Positive Control 5

Mouse lung

Positive Control 6

Mouse heart

NCBI Official Name

Catenin (cadherin-associated protein), alpha 1, 102kDa

NCBI Organism

Homo sapiens

Other Product Names

Catenin alpha-1, Alpha E-catenin, Cadherin-associated protein, Renal carcinoma antigen NY-REN-13, CTNNA1

Tested Applications

WB, IHC, IP

Physical Properties

Liquid

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