NRF1 Antibody
Product Specifications
Background
This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2) -like 1' which has an official symbol of NFE2L1.
NCBI Gene ID
4899
Swiss Prot
Q16656
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 240-449 of human NRF1 (NP_001035199.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Transcription
Purification
Affinity purification
Positive Control
K-562
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 68kDa
Fragment
IgG
Symbol
NRF1
Positive Control 2
MCF7
Positive Control 3
Mouse liver
Positive Control 4
Rat kidney
Positive Control 5
Rat testis
NCBI Official Name
Nuclear respiratory factor 1
NCBI Organism
Homo sapiens
Other Product Names
NRF1, ALPHA-PAL
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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