PKP2 Antibody
Product Specifications
Background
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.
NCBI Gene ID
5318
Swiss Prot
Q99959
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 578-837 of human PKP2 (NP_001005242.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
Raji
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 95-105kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PKP2
Positive Control 2
Mouse kidney
Positive Control 3
Mouse liver
Positive Control 4
Rat kidney
NCBI Official Name
Plakophilin 2
NCBI Organism
Homo sapiens
Other Product Names
Plakophilin-2, MGC177501, ARVD9, plakophilin 2, PKP2
Tested Applications
WB
Physical Properties
Liquid
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