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S100A11 Antibody, KO Validated

Product Specifications

Background

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.

NCBI Gene ID

6282

Swiss Prot

P31949

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human S100A11 (NP_005611.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Validation

Antibody is Knockout validated.

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

BxPC-3

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 12kDa

Fragment

IgG

Symbol

S100A11

Positive Control 2

BT-474

Positive Control 3

LOVO

Positive Control 4

22Rv1

Positive Control 5

SKOV3

Positive Control 6

THP-1

NCBI Official Name

S100 calcium binding protein A11

NCBI Organism

Homo sapiens

Other Product Names

HEL-S-43, MLN7S100C, protein S100-A11, MLN 7calgizzarin, epididymis secretory protein Li 43, metastatic lymph node gene 70 protein, protein S100-C

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

Frequently Asked Questions

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