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PLA2G1B Antibody

Product Specifications

Background

This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs) . The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response.

NCBI Gene ID

5319

Swiss Prot

P04054

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 23-148 of human PLA2G1B (NP_000919.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

A-549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 16kDa

Fragment

IgG

Symbol

PLA2G1B

Positive Control 2

Mouse pancreas

Positive Control 3

Mouse small intestine

NCBI Official Name

Phospholipase A2, group IB (pancreas)

NCBI Organism

Homo sapiens

Other Product Names

PLA2G1B, phospholipase A2, group IB (pancreas), MGC119834, MGC119835, PLA2, PLA2A, PPLA2, group IB

Tested Applications

WB, IHC

Physical Properties

Liquid

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