PLA2G1B Antibody
Product Specifications
Background
This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs) . The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response.
NCBI Gene ID
5319
Swiss Prot
P04054
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 23-148 of human PLA2G1B (NP_000919.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 16kDa
Fragment
IgG
Symbol
PLA2G1B
Positive Control 2
Mouse pancreas
Positive Control 3
Mouse small intestine
NCBI Official Name
Phospholipase A2, group IB (pancreas)
NCBI Organism
Homo sapiens
Other Product Names
PLA2G1B, phospholipase A2, group IB (pancreas), MGC119834, MGC119835, PLA2, PLA2A, PPLA2, group IB
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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